Pharmaceutical excipientsPharmaceutical excipients refer to all pharmaceutical materials added to a prescription, other than the main drug, to solve the formability, effectiveness, stability, and safety of the preparation during prescription design. Their reliable quality and diversity are the basis for ensuring the advancement of dosage forms and preparations. Pharmaceutical excipients are excipients and additives used in the production of medicines and the preparation of prescriptions. They are substances, excluding active ingredients, that have undergone reasonable safety assessments and are included in drug formulations. In addition to shaping, acting as a carrier, and improving stability, pharmaceutical excipients also have important functions such as solubilization, cosolvency, and controlled release. They are important components that may affect the quality, safety, and effectiveness of drugs, and are the material basis for ensuring the production and development of drug preparations, playing a key role in dosage form and production.

　　With the development of China's pharmaceutical industry,Pharmaceutical excipientsand its preparations have also achieved considerable development. In 2018, the market size of pharmaceutical excipients in China reached 183.501 billion yuan, a year-on-year increase of 15.56%. The types of preparations have increased significantly. New dosage forms that could not be produced in China in the past have begun mass production, and the development and production of pharmaceutical excipients have seen significant progress. The former State Pharmaceutical Administration and pharmaceutical companies also attach great importance to the development of excipients, holding a "National Pharmaceutical Excipients Symposium" every two years, effectively promoting the development and application of new excipients, and significantly improving the quality of some pharmaceutical products. However, nationwide, ChinaPharmaceutical excipientsdevelopment is relatively late, and technological upgrades and structural adjustments are still needed to meet the needs of domestic drug production and exports.

　　The impact of medical and health system reform The reform of the medical and health system has expanded the number and extent of beneficiaries of drug security and promoted rapid growth in the pharmaceutical industry. The implementation of a basic drug bidding system for drugs in the medical and health system reform, coupled with the drug bidding system implemented over the past few years, has created a drug procurement mechanism for medical institutions that is mainly based on price competition. To adapt to this mechanism, pharmaceutical companies are trying to reduce costs, which to some extent affects the use of newer or higher-qualityPharmaceutical excipientsDespite the national price management department's preferential pricing policy for products that improve drug quality and reduce sucrose use, the vast majority of pharmaceutical companies, due to a lack of corresponding technologies, including the use of better-performing pharmaceutical excipients, are still trapped in homogeneous competition.