Pharmaceutical excipientsThese are all the pharmaceutical materials, excluding the main drug, added to the prescription during the prescription design process to solve the formability, effectiveness, stability and safety of the preparation.

Depending on the classification method,Pharmaceutical excipientsthere are different classifications:

1. According to the dosage form, they can be divided into gas, liquid, semi-solid and solid states.

2. According to the chemical structure, they can be divided into acids, bases, salts, alcohols, esters, ethers, cellulose, monosaccharides, disaccharides and polysaccharides.

3. According to their uses, they can be divided into diluents, binders, disintegrants, lubricants, glidants and anti-caking agents, capsules, coating materials, wetting agents and solubilizers, etc., which is also the most commonly used classification method.

Pharmaceutical excipientsThey are the basic materials and important components of preparations, playing a key role in the production of preparations, and having a direct impact on the safety and effectiveness of drugs. Their functions are as follows:

1. Functions of excipients: After the drug is formed, it must be formulated with excipients to have a therapeutic effect. According to the different excipients, drug preparations can be divided into liquid preparations (such as solutions, injections, etc.); solid preparations (tablets, capsules, etc.); semi-solid preparations (such as ointments, gels, etc., 41 kinds; gas preparations 40 kinds, such as aerosols, sprays, etc.).

2.Pharmaceutical excipientsIt can affect the efficacy of the drug: The same drug can be prepared into different preparations with different excipients to change its efficacy.

3. Pharmaceutical excipients can affect drug absorption: Excipients are closely related to the absorption rate and dosage of drugs. For example, after dehydration of phthalate-chitosan, the mexin gel matrix particles are filled into capsules. Pharmacokinetic studies have shown that this method can avoid the peak of blood drug concentration and maintain a longer time.