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The main products are food additive microcrystalline cellulose, food additive magnesium stearate, food additive sodium carboxymethyl starch, food grade magnesium stearate, food grade sodium carboxymethyl starch microcrystalline cellulose, Magnesium stearate, sodium carboxymethyl starch, pregelatinized starch, starch, dextrin, etc.
05
2021
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02
Precautions for the use of pregelatinized starch
Pregelatinized starch is a white or off-white, moderately coarse to fine powder, odorless with a slightly characteristic taste. In the pharmaceutical field, it is commonly used as a binder, diluent, and disintegrant in oral tablets and capsules. In pharmaceutical applications, pregelatinized starch serves as a binder, diluent, and disintegrant in oral capsules and formulations. Compared to starch, pregelatinized starch increases flowability and compressibility, making it suitable as a binder in dry granulation processes. In this context, pregelatinized starch acts as a self-lubricant.
Pregelatinized StarchIt is made by gelatinizing starch and then drying and pulverizing it. It belongs to starch and is prepared again, I personally think it improves its viscosity, and its viscosity is better than starch. Pregelatinized starch is a modified starch, which is obtained by chemically or mechanically breaking starch granules partially or completely. In tablets, it is often used as a binder, diluent and disintegrant,Pregelatinized StarchIt has self-lubricating properties, and when used with other excipients, magnesium stearate should be added as a lubricant. Pregelatinized starch is harmless and non-irritating.
Pregelatinized StarchIts properties are white or off-white, moderately coarse to fine powder, odorless, with a slightly special taste. In the pharmaceutical field, it is often used as a binder, diluent and disintegrant for oral tablets and capsules. In the pharmaceutical field, pregelatinized starch is used as a binder, diluent and disintegrant for oral capsules and preparations. Compared with starch,Pregelatinized StarchIt can increase flowability and compressibility, and is used as a binder in dry granulation tableting. Among them, pregelatinized starch acts as a self-lubricant. The solubility of pregelatinized starch is insoluble in organic solvents, and slightly soluble or soluble in cold water depending on the degree of gelatinization. Pregelatinized starch is sieved into stirred cold water to obtain starch paste, partPregelatinized Starchis soluble in cold water by percentage10-20。
Pregelatinized StarchUsage precautions:
1Storage methods should pay attention to storing in a cool, dry and ventilated place;
2When used as a dry binder for direct compression of powders, alkali metal salts of stearic acid (such as magnesium stearate) should be used as little as possible or not at all as lubricants, so as not to affect the hardness of the tablets. If necessary, stearic acid can be used as a lubricant, and stearic acid has less adverse effect on the hardness of tablets.
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